How is infertility depends on the cause, your age, how long they have been sterile and personal preferences. While some women only need one or two treatments to restore fertility, it is possible that several types of treatment may be needed before they can conceive.
Treatments may be trying to restore fertility - with drugs or surgery - or assist in the playback with sophisticated techniques.
Restoration of fertility: the stimulation of ovulation with fertility drugs
Fertility drugs that regulate or induce ovulation, is the main treatment for women who are infertile due to ovulation disorders. Generally, they work as natural hormones - follicle stimulating hormone (FSH) and luteinizing hormone (LH) - to induce ovulation.
Using fertility drugs carries some risk:
Getting pregnant with twins or other multiples. Oral medications have a relatively low risk of multiple (less than 10 percent), but the odds rise to about 15-20 percent of injectable drugs. Usually, the more you are carrying fetuses, the greater the risk of preterm delivery, low birth weight and development problems later. Sometimes the amount or timing of medication should be changed to try to reduce the risk of multiples. Counseling sessions may be canceled if a doctor detects the development of too many follicles, which could lead to ovulation of more than one egg.
Development of the enlargement of the ovary. The ovarian hyperstimulation syndrome (OHSS) is a condition that may result from the use of fertility drugs. In response to the medication, your ovaries overstimulated. In addition to the development of ovarian enlargement, you may experience abdominal pain and bloating, gastrointestinal problems and shortness of breath. Signs and symptoms may develop while you are with the induction of ovulation or during the early stages of pregnancy.
There are fertility drugs in an abnormal number of LH and FSH production. These medications include:
Clomiphene citrate (Clomid, Serophene). This drug is taken orally and stimulates ovulation in women with PCOS or other ovulatory disorders. It causes the pituitary gland to release more FSH and LH, which stimulates the growth of an ovarian follicle containing an egg. Clomiphene citrate also improves fertility in women ovulate normally and is often used as a first for unexplained infertility.
Gonadotropins. Instead of stimulating the pituitary to release more hormones, these treatments directly stimulate the ovaries. Often, medications are used in combination with gonadotropin intrauterine insemination (IUI) - a procedure in which sperm is injected into the uterus through a thin tube (catheter) - to increase the chances of pregnancy. Gonadotropin medications include:
Human menopausal gonadotropin or hMG (Repronex, Menopur). This medicine is injected into women who do not ovulate on their own because of the lack of the pituitary gland to stimulate ovulation. HMG contains FSH and LH, and directly stimulates the ovaries to ovulate.
Follicle stimulating hormone or FSH (Gonal-F, Follistim, Bravelle). FSH acts by stimulating the ovaries to produce mature follicles.
Human chorionic gonadotropin or hCG (Ovidrel, Pregnyl). Used in combination with clomiphene, HMG or FSH, this drug stimulates the follicle to release an egg (ovulation).
Metformin (Glucophage). This oral drug is used when insulin resistance is known or suspected cause of infertility, usually in women diagnosed with PCOS. Metformin improves insulin resistance, normalizes insulin and make it more likely ovulation.
Letrozole (Femara). Letrozole belongs to a class of drugs called aromatase inhibitors. Letrozole is also used to treat some breast cancers, can induce ovulation. However, the effectiveness of the drug on early pregnancy are not yet known, so this drug is not used for ovulation induction as often as others.
Fertility Restoration Surgery
Various surgical procedures can correct problems or enhance female fertility. These include:
Tissue samples. This surgery removes the endometrial tissue or pelvic adhesions or with laser ablation, which can improve your chances of getting pregnant.
Reversal of sterilization (microscopic). After the woman had a tubal ligation for permanent contraception (tubal ligation), surgery can be done to reconnect and restore fertility. Your doctor will determine if you are a good candidate for surgery.
Tubal surgery. If the fallopian tubes are blocked or filled with fluid (called hydrosalpinx), tubal surgery may improve your chances of getting pregnant. Laparoscopic surgery is performed to remove clamps, tubes to expand or create a new opening of the tube. Tubal surgery is more effective when the blocked or narrowed part of the tube is closer to the ovaries to the uterus. Obstruction of the tube near the uterus can increase the risk of ectopic pregnancy. In these and other serious cases, the blockage or hydrosalpinx, removal of the tube (salpingectomy) can improve the prospects of pregnancy with in vitro fertilization.
Help on reproduction: in vitro fertilization
This powerful technique is the recovery of mature eggs from a woman, fertilized with sperm from a man in a dish in a laboratory and the embryos are transferred into the uterus of three to five days after fertilization. In vitro fertilization (IVF) is often recommended when the fallopian tubes are blocked. It is also widely used for a number of conditions such as endometriosis, unexplained infertility, cervical infertility, male infertility and ovulation disorders. IVF increases the chances of having twins or multiple if more than one embryo is transferred to the uterus. IVF requires frequent blood tests and daily hormone injections.
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